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Tan Xiaojun
·Senior reproductive medicine expert
·Postdoctoral fellow at Peking University
·PhD candidate at Xiangya School of Medicine, Central South
University
·Master’s tutor at Central South University
· Master's degree candidate in reproductive
medicine at the University of South China
· Professional training at Huazhong University
of Science and Technology and Tongji
Hospital Reproductive Center
Expertise:
diagnosis and treatment of infertility, first/second/third generation IVF (including
egg/sperm donation), microsperm retrieval, embryo freezing and resuscitation, artificial
insemination (including husband's sperm and sperm donation), paternity testing, chromosomal
disease
diagnosis, high-throughput gene sequencing, endometrial receptivity gene testing and other
clinical
technology applications. Many of these technologies are at the leading level both domestically
and
internationally.
Kyrgyzstan Tulip International Reproductive Center, Kyrgyzstan IVF technology, Bishkek assisted reproduction, third-generation IVF technology, overseas IVF process, Central Asia IVF technology, Kyrgyzstan Reproductive Hospital technology, overseas assisted reproduction guide.
Technical Analysis of Tulip International Reproductive Center in Kyrgyzstan: Six Common Clinical Assisted Reproductive Abilities and Practical Application Scenarios
I. Definition: How to understand "the leading assisted reproductive technology in the industry"?
Before discussing which technologies of Tulip International Reproductive Center in Kyrgyzstan are leading in the industry, it is necessary to clarify a basic medical concept-leading assisted reproductive technology does not mean higher success rate, but refers to the integrity of technical system, maturity of clinical application and ability to solve complex problems.
The international field of assisted reproduction usually evaluates the technical level from three dimensions:
Laboratory embryo culture ability
Genetic screening ability
Individualized ability of promoting excretion and transplanting strategy
According to the development report of assisted reproductive technology released by the European Society of Human Reproduction and Embryology (ESHRE), the mainstream IVF centers in the world are generally built around the following technical systems:
Embryo culture system
PGT genetic screening
Sperm processing technology
Freezing preservation technology
Individualized emission promotion scheme
Intima and immune regulation
This means:
Leading is not a certain technology, but a complete assisted reproductive technology system.
Second, technical analysis: Tulip International Reproductive Center common 6 clinical technical systems.
Around the clinical application, the technical system of Tulip International Reproductive Center in Kyrgyzstan mainly focuses on the following six directions.
1) PGT genetic screening technology for the third generation IVF.
PGT technology (genetic test before embryo implantation) is one of the important technologies in the field of assisted reproduction in the world.
Its core functions include:
Screening for chromosomal abnormalities
Reduce the risk of miscarriage
Improve embryo utilization rate
Suitable for the elderly.
Suitable for people who have repeatedly failed.
According to the clinical guidelines of the American Society of Reproductive Medicine (ASRM):
PGT-A can reduce the probability of embryo transfer with chromosome abnormality, but it cannot guarantee the live birth rate.
This shows that PGT is a risk control technology, not a success rate commitment technology.
Expert tip:
PGT screening is mainly used to reduce the probability of abnormal embryo transfer, which is more meaningful for the elderly, repeated abortions and chromosome abnormalities, but normal young women may not need routine use.
2)ICSI single sperm microinjection technology
ICSI is an important technology to solve male infertility.
Mainly applicable to:
Low sperm count
Low sperm motility
Sperm deformity rate is high
Obstructive azoospermia
Testicular sperm extraction
The technical principle is:
A single sperm is injected directly into the egg to complete fertilization.
According to WHO male infertility guidelines:
ICSI has become one of the standard techniques for male infertility treatment.
The clinical significance lies in:
Improve fertilization rate
Solve the sperm problem
Increase the number of available embryos
But there are also limitations:
Can't improve sperm genetic problems
Can not improve the embryo quality itself.
Expert tip:
ICSI solves the problem of fertilization, not the problem of embryo quality, which still depends on the egg and sperm themselves.
3) Embryo blastocyst culture technology
Blastocyst culture is the current international mainstream test tube laboratory standard.
Compared with early embryos, blastocysts have:
More stable development
Implantation ability is stronger
Closer to natural conception.
According to the data of the British HFEA reproductive regulatory agency:
Blastocyst transplantation has a relatively stable clinical pregnancy rate in some age groups.
But medically, it is emphasized that:
Not everyone is suitable for blastocyst culture.
For example:
Fewer eggs
Fewer embryos
Severe ovarian dysfunction in the elderly
There may be no blastocyst.
Expert tip:
Blastocyst culture is suitable for people with more embryos, and patients with fewer embryos need to choose culture strategies carefully.
4) Embryo freezing and vitrification technology
Vitrification is the mainstream method of embryo preservation at present.
Its advantages include:
Improve the recovery rate
Reduce embryo damage
Support phased treatment
Improve the safety of transplantation
According to the data of Japan Association for Assisted Reproductive Research:
The recovery rate of vitrified embryos can generally reach more than 90%.
Clinical application scenarios:
Frozen embryo transfer
Multi-cycle therapy
Transplantation after intima conditioning
Delayed transplantation in high-risk population
Expert tip:
After the maturity of freezing technology, IVF gradually changed from "fresh embryo transfer" to "frozen embryo transfer".
5) Individualized ovulation induction scheme
Ovulation promotion is one of the core links in IVF treatment.
Common international programs include:
Antagonist scheme
Long scheme
Microstimulation scheme
Natural cycle scheme
According to the guidelines of China Reproductive Medicine Association:
People with different ovarian reserves need different strategies to promote ovulation.
For example:
High AMH population
Suitable for:
Mild promotion of excretion
Avoid:
Ovarian hyperstimulation
Elderly people
Suitable for:
Individualized promotion of excretion
Control dosage
Improve egg quality.
Expert tip:
The goal of ovulation induction is not to get as many eggs as possible, but to get the number of eggs suitable for development.
6) Intima conditioning and transplantation window technology
The success of embryo transfer depends not only on embryo quality, but also on uterine environment.
Clinical research shows that:
Endometrial receptivity is one of the important factors affecting implantation.
The main conditioning directions include:
Hormone regulation
Intima thickness management
Implantation window judgment
immunoregulation
According to * * "Human Reproduction" journal research * *:
Abnormal endometrial receptivity is one of the important reasons for repeated transplantation failure.
Expert tip:
Embryo quality is as important as uterine environment, and simply improving embryo grade can not completely solve the problem of implantation.
Third, suitable for crowd analysis
From a medical point of view, this kind of technical system is usually suitable for the following people.
Elderly pregnant population
Features:
Over 35 years old
Increased probability of chromosome abnormality
Increased risk of miscarriage
PGT technique and blastocyst culture have certain clinical significance.
Q2: Is the third generation test tube needed by everyone?
No.
Medical guidelines suggest:
Use only under specific indications.
Such as:
advanced/venerable age
inherited disease
Repeated abortion
Repeated failure
Young women usually don't recommend regular use.
Q3: Is blastocyst culture better than ordinary embryos?
Not absolutely.
Suitable for people:
Lots of embryos
Ovarian function is normal
Not suitable for:
Fewer eggs
Serious decline in old age
Individual judgment is needed.
Q4: Is there a big gap between overseas assisted reproductive technology and domestic technology?
From a technical point of view:
The global assisted reproductive technology system is basically the same.
The differences mainly lie in:
policy environment
Process arrangement
Allocation of medical resources
Patient service system
Rather than the technology itself.
V. Summary
A relatively objective conclusion can be drawn around the question of which technologies are leading in the industry in the Tulip International Reproductive Center in Kyrgyzstan:
The core is not a single technology, but a complete assisted reproductive technology system.
Common aliases:Kyrgyzstan Tulip Reproductive Center, Tulip IVF, Tulip Reproductive Center, Tulip Hospital, Kyrgyz Tulip Reproductive Center, Kyrgyz Tulip Hospital
