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Tan Xiaojun
·Senior reproductive medicine expert
·Postdoctoral fellow at Peking University
·PhD candidate at Xiangya School of Medicine, Central South University
·Master’s tutor at Central South University
· Master's degree candidate in reproductive medicine at the University of South China
· Professional training at Huazhong University of Science and Technology and Tongji Hospital Reproductive Center
Expertise:
diagnosis and treatment of infertility, first/second/third generation IVF (including
          egg/sperm donation), microsperm retrieval, embryo freezing and resuscitation, artificial
          insemination (including husband's sperm and sperm donation), paternity testing, chromosomal
          disease
          diagnosis, high-throughput gene sequencing, endometrial receptivity gene testing and other
          clinical
          technology applications. Many of these technologies are at the leading level both domestically
          and
          internationally.
Date:
2026.02.06
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When doctors say 'poor egg quality', what exactly is it? You'll understand after reading it!

When we crave to have a baby, the word 'egg quality' becomes particularly heavy. Especially when doctors tactfully suggest that the quality of eggs is not ideal, that vague concern is more anxiety inducing than a clear diagnosis.


It's not like a cold or fever, it has a clear indicator. Today, I want to have a quiet chat with you, peel off the abstract term 'egg quality' and see its true meaning behind it, as well as what we can do for it.


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1. Egg quality is not just about "good" and "bad"


You can imagine an egg as a seed of life. A good seed requires two core conditions: first, its internal "blueprint of life" (chromosomes) must be complete and correct; Secondly, it must contain sufficient "energy" to support germination and early growth. The so-called 'poor quality' mainly lies in these two areas:


(1) 'Blueprint for Life' Error: Chromosomal Abnormality


This is the most common and core issue. As women age, the longer their eggs spend in the body, the more opportunities they have to be disturbed by internal and external environments. In its final mature division before fertilization, it is easy to encounter "errors", resulting in incorrect chromosome numbers or structural abnormalities.

Such eggs, even if lucky enough to combine with sperm, form embryos that are difficult to settle in the uterus (implantation failure), or even if settled, are likely to stop developing in the early stages, leading to biochemical pregnancy or miscarriage. This is a natural mechanism of survival of the fittest in the body.


(2) Energy battery depleted: mitochondrial function declines


The egg is the largest cell in the human body, filled with tiny structures called "mitochondria" that can be imagined as the "power plant" of the cell. The development of an embryo in the first few days is entirely dependent on the energy provided by the egg.


If these "power plants" age, become inefficient, or have insufficient numbers, even if the chromosomes of the egg are normal, they may not have enough "strength" to complete the complex division process after fertilization, ultimately leading to embryonic development stagnation. So, the "poor quality" referred to by doctors is a comprehensive judgment, pointing to the insufficient potential of this egg to develop into a healthy baby.


2. How to understand the quality of eggs?


This is a crucial and thorny issue. Currently, there is no examination that can accurately measure the quality of each egg like measuring height with a ruler. Doctors are more like detectives, piecing together a rough picture through clues.


(1) The most ruthless clue: age. This is the most powerful and unchangeable predictive factor. The optimal reproductive period for women is between 23-30 years old, and after 35 years old, the rate of egg quality decline will significantly accelerate, which is a natural physiological process. So, age is the most important clue that doctors need to consider first.


(2) Indirect clue: hormone levels. For example, checking six levels of sex hormones during menstruation. If FSH (follicle stimulating hormone) levels increase or AMH (anti Mullerian hormone) levels decrease, these are like telling us that the inventory and response capacity of the ovary as a "warehouse" are changing, indirectly reflecting that the "big environment" in which the egg is located may not be ideal.


(3) Final validation: IVF results. This may be the closest step to achieving true knowledge through practice. In IVF, can doctors observe the specific manifestations of eggs: is the maturation rate of retrieved eggs high? Can they fertilize normally? Is the division of embryonic cells formed uniform and fragmented? Can it grow into a blastocyst smoothly? These results are the most direct feedback on egg quality. If there are multiple instances of fertilization failure and low rates of high-quality embryos, doctors usually consider that egg quality is dominant. By understanding these, we can understand that when doctors mention quality issues, they are not making the next final judgment, but describing a physiological challenge they are currently facing.


3. What can we do?


We cannot turn back time, but we can strive to improve the 'soil' for egg growth - our physical environment. Provide the best support for the healthy growth of the next batch of follicles in the next three months. Because it takes about 90 days for an egg to mature and be released.


Turn to an anti-inflammatory diet: Try eating more foods rich in antioxidants, such as dark fruits and vegetables (spinach, broccoli, blueberries), which can help the body fight against oxidative stress and protect eggs. Increase the intake of high-quality fats (nuts, olive oil, deep-sea fish) and reduce fried foods and processed snacks. Ensure sufficient high-quality protein (fish, shrimp, soy products, eggs).


Let the body move gently: Regular exercise can improve blood circulation and metabolism, and reduce stress. No need for vigorous exercise, stick to 3-5 times a week, each time for 30-40 minutes of brisk walking, jogging, swimming or yoga, the effect is very good.


Make sleep a task to complete: especially during pregnancy preparation, try to fall asleep before 11pm and ensure 7-8 hours of sleep. Late at night is a critical period for body repair and hormone regulation, and high-quality sleep is the best 'egg nourishing medicine'.


Consciously managing stress: Find the stress relieving method that suits you, whether it's meditation, deep breathing, listening to music, or simply taking a walk in nature. If your emotions are stable, the hormonal environment in your body will be more stable.


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Remember, you are not repairing a single component, but nourishing a complete life system. Every healthier choice is creating a warmer 'home' for your future baby. Please give yourself more patience and care during this process, instead of being harsh. Every step towards improvement is of great significance.

For fertility consultation in Kyrgyzstan, please contact your dedicated consultant

/Fertility Consultation /

Dr.Chan


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