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Tan Xiaojun
·Senior reproductive medicine expert
·Postdoctoral fellow at Peking University
·PhD candidate at Xiangya School of Medicine, Central South University
·Master’s tutor at Central South University
· Master's degree candidate in reproductive medicine at the University of South China
· Professional training at Huazhong University of Science and Technology and Tongji Hospital Reproductive Center
Expertise:
diagnosis and treatment of infertility, first/second/third generation IVF (including
          egg/sperm donation), microsperm retrieval, embryo freezing and resuscitation, artificial
          insemination (including husband's sperm and sperm donation), paternity testing, chromosomal
          disease
          diagnosis, high-throughput gene sequencing, endometrial receptivity gene testing and other
          clinical
          technology applications. Many of these technologies are at the leading level both domestically
          and
          internationally.
Tags:
Embryo Transfer, Kyrgyzstan Tulip International Reproductive Center, Overseas IVF, Single Child Fertility Assistance Institution, Cross border Fertility Assistance
Date:
2025.11.28
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Can azoospermia only supply sperm? How to achieve self fertilization with IVF technology?

For many male patients diagnosed with 'azoospermia', these three words often mean a fertility judgment.


However, the progress of medicine always opens up new paths in despair. From obstructive to non obstructive, from repeated surgical failures to ultimately obtaining healthy embryos, the distance in between may only be the application of one core technology.


Today, based on the clinical experience of Tulip International Reproductive Center, we will answer the question of how azoospermia patients can achieve "self fertilization and assisted reproduction" through assisted reproductive technology in Kyrgyzstan through a real case.


Tulip International Reproductive Center, solving the problem of azoospermia

郁金香国际生殖中心,解决无精症问题

Q1:Does the diagnosis of azoospermia mean that one must give up having blood descendants?

The answer is negative. In clinical practice, azoospermia is divided into obstructive and non obstructive types.


Obstructive azoospermia: Similar to a blockage in a water pipeline, the factory (testicle) is still producing but cannot be transported out. In this case, sperm can usually be obtained through aspiration.


Non obstructive azoospermia: Similar to "factory shutdown or extremely low production", this is a difficult point in treatment.


However, in the practice of reproductive medicine in Kyrgyzstan, even patients with non obstructive azoospermia or those who have failed conventional micro TESE procedures may still find extremely rare "fish in the net" in semen sediment. As long as even a few sperm with normal morphology can be found and combined with ICSI (intracytoplasmic sperm injection) technology, there is a chance to cultivate embryos.


Q2: Conventional puncture cannot find sperm. What special methods does the Kyrgyzstan laboratory have?

In regular hospitals, if a large number of sperm are not directly visible in the field of vision, it is often judged as' azoospermia '. But at the Tulip International Reproductive Center, we use a more sophisticated 'rare sperm centrifugal capture technology'.


This is not a simple microscopic observation, but requires great patience and time from embryologists. By performing multiple centrifugation treatments on semen, the sediment is scanned layer by layer under a microscope at hundreds or even thousands of times magnification.


For patients with severe oligoasthenozoospermia or occult azoospermia, this "carpet search" often reveals those deeply hidden sperm. In addition, the application of single sperm freezing technology ensures that even if only one sperm is found, it can be safely stored without waiting until the day of egg retrieval to try luck.


Q3: [Real case] After 8 years of seeking medical treatment, how did I survive after failing to perform microsurgical sperm extraction?

In order to provide a more intuitive understanding of this process, we share the experience of a patient who successfully "landed" at the Tulip International Reproductive Center.


Patient background: Mr. L, who has been preparing for pregnancy for 8 years. At first, it was misdiagnosed as obstructive azoospermia and underwent multiple surgeries such as vasography and bilateral epididymal anastomosis, but no results were found. In 2018, he took a desperate step and underwent a highly invasive Micro TESE procedure. Although the pathological report showed the presence of spermatogenic cells, no usable sperm was actually extracted. That was his most desperate moment, when the local doctor declared that he could only supply sperm.


A turning point occurred: In early 2024, with the mentality of "treating a dead horse as a living horse doctor", Mr. L contacted the Tulip International Reproductive Center in Kyrgyzstan. He had planned to undergo his final puncture, but if it failed, he would accept the sperm supply plan.


Treatment process: After arriving in Kyrgyzstan, the laboratory director carefully evaluated his past medical records and recommended suspending invasive surgery and attempting deep semen analysis at the laboratory level (i.e., the aforementioned fine centrifugation technique).


Mr. L originally had no hope, after all, all the previous microsurgery had failed. However, a miracle occurred under the microscope in the laboratory - the embryologist discovered three viable sperm in the processed semen sediment!


The medical team pursued the victory and collected a total of 27 usable sperm using single sperm freezing technology in several subsequent semen treatments.


On the day of egg retrieval, in conjunction with the wife's 24 eggs, the laboratory team utilized advanced ICSI technology for fertilization. In the end, 7 high-quality blastocysts were successfully obtained at the Tulip International Reproductive Center. At present, they are waiting for Kyrgyzstan's caring expectant mothers to undergo transplantation.


Q4: Why didn't the previous microsurgery find it, but semen analysis found it instead?

This is a common cognitive misconception. Although microscopic sperm extraction is one of the gold standards, it involves searching for "germinal foci" in specific areas of the testes, which poses a probability issue.


And semen is the final product of the overall spermatogenic function of the testes. Mr. L's case illustrates that even in non obstructive azoospermia, there may be very small amounts of focal spermatogenesis in the testes. These rare sperm may be intermittently expelled from the body.


The advantage of Tulip International Reproductive Center is that we will not easily give up any samples. Our laboratory team is willing to spend hours searching for that glimmer of hope, rather than simply giving a report of 'no sperm seen'.


Q5: What are the suggestions for patients with azoospermia who have not been cured for a long time?

Do not blindly undergo surgery: frequent punctures and surgeries can damage testicular tissue, causing irreversible damage. Before performing invasive procedures, conduct a thorough laboratory semen analysis.


Choosing a professional laboratory: Often, it's not that you don't have sperm, but rather that the laboratory's technology and patience are insufficient. It is crucial to choose institutions like Tulip International Reproductive Center that have single sperm freezing and rare sperm capture technologies.


Psychological adjustment: Sperm production function is influenced by emotions. After giving up anxiety and coming to Kyrgyzstan to relax, Mr. L's sperm quality showed a slight improvement.


In Kyrgyzstan, the legal assisted reproductive policy combined with advanced reproductive technology has lit up hope for countless families like Mr. L. With just one sperm, we can create a complete home for you.


For fertility consultation in Kyrgyzstan, please contact your dedicated consultant

/Fertility Consultation /

Dr.Chan


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